Product name:Human anti-Sa-antibody ELISA Kit
Description:
Anti-Sa antibodies are detected in the serum of 20–47% of patients with rheumatoid arthritis. These antibodies have a high degree of specificity for the disease, and appear to identify a subset of early rheumatoid arthritis patients destined to have aggressive and destructive disease.The Sa antigen has previously been shown to be present in synovium. anti-Sa antibodies may play a pathogenetic role in the initiation and/or persistence of rheumatoid synovitis.Antibodies directed to the Sa antigen are highly specific for rheumatoid arthritis (RA) and can be detected in approximately 40% of RA sera.