Product name:Human Casp-12 ELISA Kit
Description:
Caspase 12 is localised to the ER and is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. Caspase 12 is believed to mediate apoptosis in response to endoplasmic reticulum stress. Caspase 12 is colocalized to the ER with several proteins that are involved in Alzheimers disease including g-secretase presenilin and b-amyloid precursor protein (APP).