Product name:Human IGF-2 ELISA Kit
Description:
Insulin-like growth factor 2 (IGF-2) is one of three protein hormones that share structural similarity to insulin. In humans, the IGF2 gene is located on chromosome 11p15.5, a region which contains numerous imprinted genes. In mice this homologous region is found at distal chromosome 7. In both organisms, Igf2 is imprinted, with expression resulting favourably from the paternally inherited allele.
The major role of IGF2 is as a growth promoting hormone during gestation. It is sometimes produced in non-islet cell tumours, causing hypoglycemia (Doege-Potter syndrome).