Product name:Human Leukotriene C4 ELISA Kit
Description:
Leukotriene C4 is a leukotriene.Leukotrienes (LTs) are synthesized from membrane derived arachidonic acid.Downstream of 5-lipoxygenase in the arachidonic acid cascade, leukotriene C4 synthase (LTC4S)catalyses the conjugation of leukotriene A4 (LTA4)with reduced glutathione to form LTC4, then LTC4 convert to active metabolites LTD4 and LTE4. LTC4,LTD4 and LTE4, which are called cysteinyl leukotrienes (CysLTs), are potent proinflammatory mediators of asthma. LTC4S is the key enzyme involved in the formation of CysLTs.