Product name:Human MCT ELISA Kit
Description:
Tryptase is the most abundant secretory granule-derived serine proteinase contained in mast cells that has recently been used as a marker for mast cell activation. Mast cell tryptase differs markedly from other serine proteases in many of its biochemical feature. It has two or more subunits which associate noncovalently as catalytically active tetramers and appears to be stored and released as an active enzyme rather than as a zymogen. Tryptase is involved with allergenic response and is suspected to act as a mitogen for fibroblast lines. Elevated levels of serum tryptase occur in both anaphylactic and anaphylactoid reactions, but a negative test does not exclude anaphylaxis.