Product name:Human Perforin/Pore-forming protein,PF/PFP ELISA Kit
Description:
Perforin is a cytolytic protein found in the granules of CD8 T-cells and NK cells. Upon degranulation, perforin inserts itself into the target cell's plasma membrane, forming a pore. The lytic membrane inserting part of perforin is the MACPF domain. This region shares homology with cholesterol dependent cytolysins from Gram positive bacteria.