Product name:Human protein kinase B ELISA Kit
Description:
Specifically recognizes PKB when it is dephosphorylated at Serine 473 (epitope: QFSYSA). The PKB (RAC/akt) protein kinases are a family of second messenger ? regulated serine/threonine kinases. Three mammalian isoforms (alpha, beta, gamma) have been identified so far, the alpha-isoform being the cellular homologue of the v-akt oncogene. Stimulation of cells with growth factors leads to activation of PKB by a phosphoinositide-3-kinase dependent signal transduction pathway.