Product name:Human sICAM-1 ELISA Kit
Description:
Intercellular Adhesion Molecule-1 (ICAM-1) is a member of the immunoglobulin supergene family and functions as a ligand for integrin alphaLbeta2 or Lymphocyte Function-Associated Antigen-1 (LFA-1), a member of the leukocyte integrin family which mediates lymphocyte adhesion.
ICAM-1 is a single-chain glycoprotein with a polypeptide core of 55kDa expressed on non-hematopoietic cells of many lineages including vascular endothelial cells, thymic epithelial cells, other epithelial cells and fibroblasts, and on hematopoietic cells such as tissue macrophages, mitogen-stimulated T-lymphoblasts, germinal center B-cells and the dendritic cells from tonsils, lymph nodes and Peyer's patches.