Product name:HumansTRAIL ELISA Kit
Description:
Tumor necrosis factor-related apoptosis inducing ligand (TRAIL)/Apo2L is a type II transmembrane protein that was identified and cloned based on its sequence homology with members of the TNF ligand family.TRAIL is expressed constitutively in many tissues such as liver, lung, placenta, kidney, spleen, peripheral lymphocyte, etc. TRAIL induces cancer apoptosis independently of p53 gene mutation. TRAIL may also play roles in immune responses, autoimmune disorders and HIV infections. TRAIL can interact with five different members of the TNF receptor superfamily, two of which contain a death domain, and can mediate an apoptotic response. TRAIL may also be a marker for progression of cancer.