Product name:Human TSP-1 ELISA Kit
Description:
Thrombospondin-1 (TSP-1) is a 150 - 180 kDa charter member of the thrombospondin family of extracellular matrix proteins. Human TSP-1 is synthesized as an 1170 amino acid (aa) precursor that contains an 18 aa signal sequence and 1152 aa mature molecule. The mature molecule has been described as containing three distinct regions that create the shape of a dumbbell.TSP-1 is secreted as a disulfide-linked 450 kDa homotrimer. The cysteines responsible lie just N-terminal to the first type I TSP repeat. Mature human TSP-1 is 61% aa identical to human TSP-2. It is also 95%, 97% and 95% aa identical to mouse, dog and rat TSP-1, respectively.