Product name:Rat Macrophage Migration Inhibitory Factor,MIF ELISA Kit
Description:
MIF (or macrophage migration inhibitory factor) was the first lymphokine/cytokine to be recognized in the pregenomics era.Regardless, it is one of the least understood of all inflammatory mediators. rat MIF is a 12.5 kDa, 115 amino acid (aa) nonglycosylated polypeptide that is synthesized without a signal sequence.Secretion occurs nonclassically via an ABCA1 transporter.MIF has proinflammatory cytokine activity centered on aa’s 49 - 65.rat MIF apparently acts through CD74 and CD44,likely in some form of trimeric interaction. rat MIF is active on human cells, while human MIF is active on rat cells. rat MIF is 99%, 84%, 90%, and 90% aa identical to rat, porcine, bovine and human MIF, respectively.